Drug interactions
Levofloxacin + Temazepam
Severity: Minor
Levofloxacin and Temazepam: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Temazepam is cleared by glucuronidation, which levofloxacin does not meaningfully affect. A significant interaction is unlikely beyond additive sedation.
What this interaction means in plain words
Levofloxacin and Temazepam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Levofloxacin belongs to Anti Bacterial; Temazepam belongs to Central Nervous System.
Why it happens
No established metabolic inhibition; temazepam is eliminated mainly by glucuronidation.
What to do
No action is usually required. Monitor for unusual sedation or confusion.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Levofloxacin
- Dronedarone + Levofloxacin Contraindicated
- Ibutilide + Levofloxacin Contraindicated
- Levofloxacin + Thioridazine Contraindicated
- Levofloxacin + Vandetanib Contraindicated
- Levofloxacin + Ziprasidone Contraindicated
- Adagrasib + Levofloxacin Major
Other interactions of Temazepam
- Alprazolam + Temazepam Major
- Amobarbital + Temazepam Major
- Buprenorphine + Temazepam Major
- Butorphanol + Temazepam Major
- Carisoprodol + Temazepam Major
- Chloral hydrate + Temazepam Major
Frequently asked questions
Can I take Levofloxacin with Temazepam?
MediHelp rates the interaction as minor. Levofloxacin and Temazepam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Temazepam is cleared by glucuronidation, which levofloxacin does not meaningfully affect. A significant interaction is unlikely beyond additive sedation.
How serious is the interaction between Levofloxacin and Temazepam?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is usually required. Monitor for unusual sedation or confusion.
What other medicines interact with Levofloxacin?
MediHelp also lists interactions of Levofloxacin with, for example, Dronedarone, Ibutilide, Thioridazine. The full list is on the Levofloxacin page.
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