Drug interactions
Lincomycin + Microbiota
Severity: Moderate
Lincomycin and Microbiota: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral microbiota products contain live bacterial spores meant to restore gut flora after recurrent C. difficile infection. Antibiotics active against these organisms can reduce engraftment and effectiveness.
What this interaction means in plain words
Lincomycin and Microbiota can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Antibacterial activity reduces viability and colonization of the live microbiota spores.
What to do
Complete the antibiotic course and allow the interval stated in the product labeling before giving the microbiota product.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Lincomycin
- Atracurium + Lincomycin Major
- Cisatracurium + Lincomycin Major
- Lincomycin + Pancuronium Major
- Lincomycin + Rapacuronium Major
- Lincomycin + Rocuronium Major
- Lincomycin + Vecuronium Major
Frequently asked questions
Can I take Lincomycin with Microbiota?
MediHelp rates the interaction as moderate. Lincomycin and Microbiota can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral microbiota products contain live bacterial spores meant to restore gut flora after recurrent C. difficile infection. Antibiotics active against these organisms can reduce engraftment and effectiveness.
How serious is the interaction between Lincomycin and Microbiota?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Complete the antibiotic course and allow the interval stated in the product labeling before giving the microbiota product.
What other medicines interact with Lincomycin?
MediHelp also lists interactions of Lincomycin with, for example, Atracurium, Cisatracurium, Pancuronium. The full list is on the Lincomycin page.
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