Drug interactions
Liothyronine + Piracetam
Severity: Minor
Liothyronine and Piracetam: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
A single case report described confusion and sleep disturbance in a patient taking piracetam with thyroid hormone. A causal link is uncertain and the interaction is poorly characterized.
What this interaction means in plain words
Liothyronine and Piracetam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Liothyronine belongs to Endocrine; Piracetam belongs to Gastrointestinal Tract.
Why it happens
The mechanism is not established; possible additive CNS stimulation.
What to do
Monitor for confusion, irritability and sleep disturbance and review thyroid status. Reassess the piracetam if symptoms appear.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Piracetam
- Cilostazol + Piracetam Moderate
- Dipyridamole + Piracetam Moderate
- Eptifibatide + Piracetam Moderate
- Piracetam + Prasugrel Moderate
- Piracetam + Tirofiban Moderate
- Clopidogrel + Piracetam Minor
Other interactions of Liothyronine
- Alogliptin-metformin + Liothyronine Moderate
- Amitriptyline + Liothyronine Moderate
- Amobarbital + Liothyronine Moderate
- Canagliflozin-metformin + Liothyronine Moderate
- Carbamazepine + Liothyronine Moderate
- Carbonyl iron + Liothyronine Moderate
Frequently asked questions
Can I take Liothyronine with Piracetam?
MediHelp rates the interaction as minor. Liothyronine and Piracetam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. A single case report described confusion and sleep disturbance in a patient taking piracetam with thyroid hormone. A causal link is uncertain and the interaction is poorly characterized.
How serious is the interaction between Liothyronine and Piracetam?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for confusion, irritability and sleep disturbance and review thyroid status. Reassess the piracetam if symptoms appear.
What other medicines interact with Piracetam?
MediHelp also lists interactions of Piracetam with, for example, Cilostazol, Dipyridamole, Eptifibatide. The full list is on the Piracetam page.
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