Drug interactions
Liraglutide + Prednisone
Severity: Moderate
Liraglutide and Prednisone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Glucocorticoids cause hyperglycemia and insulin resistance, which can offset the glucose-lowering effect of liraglutide. Glycemic control may deteriorate in patients with diabetes.
What this interaction means in plain words
Liraglutide and Prednisone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Liraglutide belongs to Endocrine; Prednisone belongs to Endocrine.
Why it happens
Pharmacodynamic antagonism through glucocorticoid-induced insulin resistance and increased hepatic gluconeogenesis.
What to do
Monitor blood glucose more frequently when starting, increasing or stopping prednisone, and adjust antidiabetic therapy accordingly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Prednisone
- Bcg vaccine live + Prednisone Contraindicated
- Measles vaccine + Prednisone Contraindicated
- Mifepristone + Prednisone Contraindicated
- Prednisone + Radium-223 dichloride Contraindicated
- Prednisone + Smallpox vaccine live Contraindicated
- Adenovirus types 4 and 7 live + Prednisone Major
Other interactions of Liraglutide
Frequently asked questions
Can I take Liraglutide with Prednisone?
MediHelp rates the interaction as moderate. Liraglutide and Prednisone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Glucocorticoids cause hyperglycemia and insulin resistance, which can offset the glucose-lowering effect of liraglutide. Glycemic control may deteriorate in patients with diabetes.
How serious is the interaction between Liraglutide and Prednisone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose more frequently when starting, increasing or stopping prednisone, and adjust antidiabetic therapy accordingly.
What other medicines interact with Prednisone?
MediHelp also lists interactions of Prednisone with, for example, Bcg vaccine live, Measles vaccine, Mifepristone. The full list is on the Prednisone page.
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