Drug interactions
Liraglutide + Ziprasidone
Severity: Minor
Liraglutide and Ziprasidone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Antipsychotics, including ziprasidone, can disturb glucose regulation, which may partly offset the glucose-lowering effect of liraglutide. Ziprasidone has a comparatively low metabolic liability, so the effect is usually small.
What this interaction means in plain words
Liraglutide and Ziprasidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Liraglutide belongs to Endocrine; Ziprasidone belongs to Central Nervous System.
Why it happens
Pharmacodynamic antagonism: antipsychotic-related impairment of glucose tolerance opposes GLP-1 receptor agonist glycemic effects.
What to do
Monitor fasting glucose and HbA1c after starting or changing ziprasidone, and adjust antidiabetic therapy if control worsens.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Liraglutide and Ziprasidone, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Ziprasidone
- Amiodarone + Ziprasidone Contraindicated
- Amitriptyline + Ziprasidone Contraindicated
- Arsenic trioxide + Ziprasidone Contraindicated
- Bedaquiline + Ziprasidone Contraindicated
- Chloroquine + Ziprasidone Contraindicated
- Citalopram + Ziprasidone Contraindicated
Other interactions of Liraglutide
Frequently asked questions
Can I take Liraglutide with Ziprasidone?
MediHelp rates the interaction as minor. Liraglutide and Ziprasidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Antipsychotics, including ziprasidone, can disturb glucose regulation, which may partly offset the glucose-lowering effect of liraglutide. Ziprasidone has a comparatively low metabolic liability, so the effect is usually small.
How serious is the interaction between Liraglutide and Ziprasidone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor fasting glucose and HbA1c after starting or changing ziprasidone, and adjust antidiabetic therapy if control worsens.
What other medicines interact with Ziprasidone?
MediHelp also lists interactions of Ziprasidone with, for example, Amiodarone, Amitriptyline, Arsenic trioxide. The full list is on the Ziprasidone page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
