Drug interactions
Lisdexamfetamine + Terbutaline
Severity: Moderate
Lisdexamfetamine and Terbutaline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs have sympathomimetic activity, so combined use can increase heart rate and blood pressure and may provoke palpitations or arrhythmias. Patients with cardiovascular disease are at greater risk.
What this interaction means in plain words
Lisdexamfetamine and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Lisdexamfetamine belongs to Central Nervous System; Terbutaline belongs to Respiratory.
Why it happens
Additive adrenergic stimulation: direct beta-agonism from terbutaline and amphetamine-mediated catecholamine release.
What to do
Monitor blood pressure, heart rate and symptoms of palpitations. Reduce the dose of one agent or choose alternatives if cardiovascular effects emerge.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Terbutaline
Other interactions of Lisdexamfetamine
- Isocarboxazid + Lisdexamfetamine Contraindicated
- Linezolid + Lisdexamfetamine Contraindicated
- Lisdexamfetamine + Phenelzine Contraindicated
- Lisdexamfetamine + Procarbazine Contraindicated
- Lisdexamfetamine + Rasagiline Contraindicated
- Lisdexamfetamine + Safinamide Contraindicated
Frequently asked questions
Can I take Lisdexamfetamine with Terbutaline?
MediHelp rates the interaction as moderate. Lisdexamfetamine and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs have sympathomimetic activity, so combined use can increase heart rate and blood pressure and may provoke palpitations or arrhythmias. Patients with cardiovascular disease are at greater risk.
How serious is the interaction between Lisdexamfetamine and Terbutaline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, heart rate and symptoms of palpitations. Reduce the dose of one agent or choose alternatives if cardiovascular effects emerge.
What other medicines interact with Terbutaline?
MediHelp also lists interactions of Terbutaline with, for example, Carvedilol, Droperidol, Fexinidazole. The full list is on the Terbutaline page.
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