Drug reference
lisdexamfetamine
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Central Nervous System (CNS Stimulants)
Mechanism of action
Sympathomimetic amine that promotes release of dopamine and norepinephrine from their storage sites in the presynaptic nerve terminals; may also block reuptake of catecholamines by competitive inhibition Prodrug of dextroamphetamine
Common side effects
- Insomnia
- Anorexia
- Headache
- Xerostomia
- Upper abdominal pain
- Irritability
Known interactions (3)
- isocarboxazid + lisdexamfetamine Contraindicated
- ergotamine + lisdexamfetamine Major
- cabergoline + lisdexamfetamine Moderate
Related conditions
Frequently asked questions
What drug class is lisdexamfetamine?
lisdexamfetamine belongs to: Central Nervous System.
How does lisdexamfetamine work?
Sympathomimetic amine that promotes release of dopamine and norepinephrine from their storage sites in the presynaptic nerve terminals; may also block reuptake of catecholamines by competitive inhibition Prodrug of dextroamphetamine
What are the common side effects of lisdexamfetamine?
Insomnia, Anorexia, Headache, Xerostomia, Upper abdominal pain, Irritability
Which drugs interact with lisdexamfetamine?
isocarboxazid, ergotamine, cabergoline
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