Drug interactions
Lurasidone + Quinidine
Severity: Minor
Lurasidone and Quinidine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
At therapeutic doses lurasidone has little QT effect, so a meaningful interaction with quinidine is not expected. A QT concern arises mainly in overdose.
What this interaction means in plain words
Lurasidone and Quinidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Lurasidone belongs to Central Nervous System; Quinidine belongs to Anti Parasitic.
Why it happens
Potential additive QT prolongation, relevant mainly at supratherapeutic lurasidone exposure.
What to do
No routine action is needed at therapeutic doses. In suspected lurasidone overdose, monitor ECG continuously.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Quinidine
- Adagrasib + Quinidine Contraindicated
- Arsenic trioxide + Quinidine Contraindicated
- Artemether / lumefantrine + Quinidine Contraindicated
- Chloroquine + Quinidine Contraindicated
- Dofetilide + Quinidine Contraindicated
- Dronedarone + Quinidine Contraindicated
Other interactions of Lurasidone
- Apalutamide + Lurasidone Contraindicated
- Atazanavir + Lurasidone Contraindicated
- Carbamazepine + Lurasidone Contraindicated
- Clarithromycin + Lurasidone Contraindicated
- Cobicistat + Lurasidone Contraindicated
- Conivaptan + Lurasidone Contraindicated
Frequently asked questions
Can I take Lurasidone with Quinidine?
MediHelp rates the interaction as minor. Lurasidone and Quinidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. At therapeutic doses lurasidone has little QT effect, so a meaningful interaction with quinidine is not expected. A QT concern arises mainly in overdose.
How serious is the interaction between Lurasidone and Quinidine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed at therapeutic doses. In suspected lurasidone overdose, monitor ECG continuously.
What other medicines interact with Quinidine?
MediHelp also lists interactions of Quinidine with, for example, Adagrasib, Arsenic trioxide, Artemether / lumefantrine. The full list is on the Quinidine page.
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