Drug interactions
Macimorelin + Prednisone
Severity: Moderate
Macimorelin and Prednisone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Macimorelin is a diagnostic stimulant of growth hormone release, and glucocorticoids can alter growth hormone secretion. Concomitant glucocorticoid exposure may therefore distort the test result and lead to misdiagnosis of growth hormone deficiency.
What this interaction means in plain words
Macimorelin and Prednisone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Macimorelin belongs to Endocrine; Prednisone belongs to Endocrine.
Why it happens
Glucocorticoids affect pituitary growth hormone secretion and may alter the response to the ghrelin agonist macimorelin.
What to do
Where clinically possible, withhold or time prednisone and allow adequate washout before macimorelin testing. Interpret the results cautiously if corticosteroid therapy cannot be interrupted.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Prednisone
- Bcg vaccine live + Prednisone Contraindicated
- Measles vaccine + Prednisone Contraindicated
- Mifepristone + Prednisone Contraindicated
- Prednisone + Radium-223 dichloride Contraindicated
- Prednisone + Smallpox vaccine live Contraindicated
- Adenovirus types 4 and 7 live + Prednisone Major
Other interactions of Macimorelin
Frequently asked questions
Can I take Macimorelin with Prednisone?
MediHelp rates the interaction as moderate. Macimorelin and Prednisone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Macimorelin is a diagnostic stimulant of growth hormone release, and glucocorticoids can alter growth hormone secretion. Concomitant glucocorticoid exposure may therefore distort the test result and lead to misdiagnosis of growth hormone deficiency.
How serious is the interaction between Macimorelin and Prednisone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Where clinically possible, withhold or time prednisone and allow adequate washout before macimorelin testing. Interpret the results cautiously if corticosteroid therapy cannot be interrupted.
What other medicines interact with Prednisone?
MediHelp also lists interactions of Prednisone with, for example, Bcg vaccine live, Measles vaccine, Mifepristone. The full list is on the Prednisone page.
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