Drug interactions
Magnesium oxide + Neomycin
Severity: Minor
Magnesium oxide and Neomycin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Aminoglycosides can cause renal magnesium wasting when absorbed, but oral neomycin has little systemic absorption. Clinical impact on magnesium is generally small.
What this interaction means in plain words
Magnesium oxide and Neomycin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Magnesium oxide belongs to Gastrointestinal Tract; Neomycin belongs to Anti Bacterial.
Why it happens
Aminoglycoside-induced tubular injury may increase urinary magnesium loss.
What to do
Monitor serum magnesium during prolonged neomycin therapy or in renal impairment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Neomycin
- Amikacin + Neomycin Major
- Amphotericin b deoxycholate + Neomycin Major
- Capreomycin + Neomycin Major
- Cidofovir + Neomycin Major
- Colistin + Neomycin Major
- Ethacrynic acid + Neomycin Major
Other interactions of Magnesium oxide
- Chloroquine + Magnesium oxide Moderate
- Ciprofloxacin + Magnesium oxide Moderate
- Dolutegravir + Magnesium oxide Moderate
- Doxycycline + Magnesium oxide Moderate
- Eltrombopag + Magnesium oxide Moderate
- Gemifloxacin + Magnesium oxide Moderate
Frequently asked questions
Can I take Magnesium oxide with Neomycin?
MediHelp rates the interaction as minor. Magnesium oxide and Neomycin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Aminoglycosides can cause renal magnesium wasting when absorbed, but oral neomycin has little systemic absorption. Clinical impact on magnesium is generally small.
How serious is the interaction between Magnesium oxide and Neomycin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum magnesium during prolonged neomycin therapy or in renal impairment.
What other medicines interact with Neomycin?
MediHelp also lists interactions of Neomycin with, for example, Amikacin, Amphotericin b deoxycholate, Capreomycin. The full list is on the Neomycin page.
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