Drug interactions
Maraviroc + Octreotide
Severity: Minor
Maraviroc and Octreotide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Octreotide has been reported to reduce CYP3A4 activity in some settings, which could raise maraviroc concentrations. The clinical significance is uncertain, but higher maraviroc exposure could increase adverse effects such as postural hypotension or hepatotoxicity.
What this interaction means in plain words
Maraviroc and Octreotide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Maraviroc belongs to Anti Virals; Octreotide belongs to Endocrine.
Why it happens
Possible reduction of CYP3A4-mediated maraviroc metabolism by octreotide, not firmly established.
What to do
No routine dose change is needed. Monitor for maraviroc adverse effects such as dizziness and liver enzyme elevation if the combination is used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Octreotide
Other interactions of Maraviroc
- Amobarbital + Maraviroc Major
- Apalutamide + Maraviroc Major
- Carbamazepine + Maraviroc Major
- Clarithromycin + Maraviroc Major
- Efavirenz + Maraviroc Major
- Enzalutamide + Maraviroc Major
Frequently asked questions
Can I take Maraviroc with Octreotide?
MediHelp rates the interaction as minor. Maraviroc and Octreotide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Octreotide has been reported to reduce CYP3A4 activity in some settings, which could raise maraviroc concentrations. The clinical significance is uncertain, but higher maraviroc exposure could increase adverse effects such as postural hypotension or hepatotoxicity.
How serious is the interaction between Maraviroc and Octreotide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine dose change is needed. Monitor for maraviroc adverse effects such as dizziness and liver enzyme elevation if the combination is used.
What other medicines interact with Octreotide?
MediHelp also lists interactions of Octreotide with, for example, Adagrasib, Amisulpride, Arsenic trioxide. The full list is on the Octreotide page.
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