Drug interactions
Maraviroc + Olanzapine
Severity: Minor
Maraviroc and Olanzapine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Maraviroc can cause postural hypotension, and olanzapine has alpha-1 blocking activity that also lowers standing blood pressure. Using both may raise the chance of dizziness, syncope and falls.
What this interaction means in plain words
Maraviroc and Olanzapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Maraviroc belongs to Anti Virals; Olanzapine belongs to Central Nervous System.
Why it happens
Additive orthostatic hypotensive effects; no significant pharmacokinetic interaction is established.
What to do
Check orthostatic blood pressure when starting or adjusting either drug and counsel patients to rise slowly.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Olanzapine
Other interactions of Maraviroc
- Amobarbital + Maraviroc Major
- Apalutamide + Maraviroc Major
- Carbamazepine + Maraviroc Major
- Clarithromycin + Maraviroc Major
- Efavirenz + Maraviroc Major
- Enzalutamide + Maraviroc Major
Frequently asked questions
Can I take Maraviroc with Olanzapine?
MediHelp rates the interaction as minor. Maraviroc and Olanzapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Maraviroc can cause postural hypotension, and olanzapine has alpha-1 blocking activity that also lowers standing blood pressure. Using both may raise the chance of dizziness, syncope and falls.
How serious is the interaction between Maraviroc and Olanzapine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check orthostatic blood pressure when starting or adjusting either drug and counsel patients to rise slowly.
What other medicines interact with Olanzapine?
MediHelp also lists interactions of Olanzapine with, for example, Amisulpride, Amoxapine, Apomorphine. The full list is on the Olanzapine page.
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