Drug interactions
Maraviroc + Olmesartan
Severity: Moderate
Maraviroc and Olmesartan: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Maraviroc can cause postural hypotension, especially in patients with renal impairment or those taking other blood pressure lowering agents. Combination with olmesartan may increase the risk of dizziness, syncope and falls.
What this interaction means in plain words
Maraviroc and Olmesartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Maraviroc belongs to Anti Virals; Olmesartan belongs to Cardiovascular.
Why it happens
Additive hypotensive effects, with maraviroc causing postural hypotension through a mechanism that is not fully defined.
What to do
Monitor orthostatic blood pressure, particularly at initiation and in patients with renal impairment. Reduce the antihypertensive dose if symptomatic hypotension occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Olmesartan
- Aliskiren + Olmesartan Contraindicated
- Olmesartan + Sparsentan Contraindicated
- Aldesleukin + Olmesartan Major
- Amifostine + Olmesartan Major
- Amiloride + Olmesartan Major
- Amlodipine-benazepril + Olmesartan Major
Other interactions of Maraviroc
- Amobarbital + Maraviroc Major
- Apalutamide + Maraviroc Major
- Carbamazepine + Maraviroc Major
- Clarithromycin + Maraviroc Major
- Efavirenz + Maraviroc Major
- Enzalutamide + Maraviroc Major
Frequently asked questions
Can I take Maraviroc with Olmesartan?
MediHelp rates the interaction as moderate. Maraviroc and Olmesartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Maraviroc can cause postural hypotension, especially in patients with renal impairment or those taking other blood pressure lowering agents. Combination with olmesartan may increase the risk of dizziness, syncope and falls.
How serious is the interaction between Maraviroc and Olmesartan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor orthostatic blood pressure, particularly at initiation and in patients with renal impairment. Reduce the antihypertensive dose if symptomatic hypotension occurs.
What other medicines interact with Olmesartan?
MediHelp also lists interactions of Olmesartan with, for example, Aliskiren, Sparsentan, Aldesleukin. The full list is on the Olmesartan page.
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