Drug interactions
Maraviroc + Sodium nitroprusside
Severity: Moderate
Maraviroc and Sodium nitroprusside: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Maraviroc can cause postural hypotension, and nitroprusside is a powerful vasodilator. Together the risk of hypotension and dizziness may increase.
What this interaction means in plain words
Maraviroc and Sodium nitroprusside can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Maraviroc belongs to Anti Virals; Sodium nitroprusside belongs to Cardiovascular.
Why it happens
Additive hypotensive effects; maraviroc's postural hypotension adds to nitroprusside vasodilation.
What to do
Monitor blood pressure during nitroprusside infusion and titrate carefully. Counsel patients on orthostatic precautions afterward.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Sodium nitroprusside
Other interactions of Maraviroc
- Amobarbital + Maraviroc Major
- Apalutamide + Maraviroc Major
- Carbamazepine + Maraviroc Major
- Clarithromycin + Maraviroc Major
- Efavirenz + Maraviroc Major
- Enzalutamide + Maraviroc Major
Frequently asked questions
Can I take Maraviroc with Sodium nitroprusside?
MediHelp rates the interaction as moderate. Maraviroc and Sodium nitroprusside can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Maraviroc can cause postural hypotension, and nitroprusside is a powerful vasodilator. Together the risk of hypotension and dizziness may increase.
How serious is the interaction between Maraviroc and Sodium nitroprusside?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure during nitroprusside infusion and titrate carefully. Counsel patients on orthostatic precautions afterward.
What other medicines interact with Sodium nitroprusside?
MediHelp also lists interactions of Sodium nitroprusside with, for example, Avanafil, Nitric oxide, Sildenafil. The full list is on the Sodium nitroprusside page.
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