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Drug interactions

Maraviroc + Telmisartan-amlodipine

Severity: Moderate

Maraviroc and Telmisartan-amlodipine: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Maraviroc can cause postural hypotension, and telmisartan-amlodipine lowers blood pressure through two mechanisms. Together they may produce additive blood pressure lowering with dizziness or fainting, especially when starting treatment or after dose changes.

What this interaction means in plain words

Maraviroc and Telmisartan-amlodipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Maraviroc belongs to Anti Virals; Telmisartan-amlodipine belongs to Cardiovascular.

Evidence level: Low

Why it happens

Additive pharmacodynamic hypotensive effects of maraviroc and the antihypertensive components.

What to do

Monitor blood pressure including standing readings when maraviroc is started or the antihypertensive dose is changed. Advise patients to rise slowly and reduce the antihypertensive dose if symptomatic hypotension occurs.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Maraviroc with Telmisartan-amlodipine?

MediHelp rates the interaction as moderate. Maraviroc and Telmisartan-amlodipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Maraviroc can cause postural hypotension, and telmisartan-amlodipine lowers blood pressure through two mechanisms. Together they may produce additive blood pressure lowering with dizziness or fainting, especially when starting treatment or after dose changes.

How serious is the interaction between Maraviroc and Telmisartan-amlodipine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure including standing readings when maraviroc is started or the antihypertensive dose is changed. Advise patients to rise slowly and reduce the antihypertensive dose if symptomatic hypotension occurs.

What other medicines interact with Telmisartan-amlodipine?

MediHelp also lists interactions of Telmisartan-amlodipine with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Telmisartan-amlodipine page.

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