Drug interactions
Measles mumps and rubella vaccine live + Secukinumab
Severity: Major
Measles mumps and rubella vaccine live and Secukinumab: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
The MMR vaccine contains live attenuated viruses, and secukinumab may reduce the vaccine response or permit vaccine-virus infection. Data in treated patients are limited.
What this interaction means in plain words
Measles mumps and rubella vaccine live and Secukinumab can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Why it happens
Immunomodulation by IL-17A blockade may reduce immunogenicity and impair control of live attenuated viruses.
What to do
Give MMR before starting secukinumab where feasible, and avoid it during therapy. Check immunity and seek specialist advice if vaccination is needed during treatment.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Measles mumps and rubella vaccine live and Secukinumab, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Secukinumab
- Adenovirus types 4 and 7 live + Secukinumab Major
- Bcg vaccine live + Secukinumab Major
- Influenza virus vaccine quadrivalent intranasal + Secukinumab Major
- Measles mumps and rubella vaccine + Secukinumab Major
- Measles mumps rubella and varicella vaccine live + Secukinumab Major
- Measles vaccine + Secukinumab Major
Frequently asked questions
Can I take Measles mumps and rubella vaccine live with Secukinumab?
MediHelp rates the interaction as major. Measles mumps and rubella vaccine live and Secukinumab can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. The MMR vaccine contains live attenuated viruses, and secukinumab may reduce the vaccine response or permit vaccine-virus infection. Data in treated patients are limited.
How serious is the interaction between Measles mumps and rubella vaccine live and Secukinumab?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give MMR before starting secukinumab where feasible, and avoid it during therapy. Check immunity and seek specialist advice if vaccination is needed during treatment.
What other medicines interact with Secukinumab?
MediHelp also lists interactions of Secukinumab with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Secukinumab page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
