Drug interactions
Measles vaccine + Secukinumab
Severity: Major
Measles vaccine and Secukinumab: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Measles vaccine is a live attenuated vaccine, and secukinumab may blunt the immune response or increase the risk of vaccine-related infection. Clinical data are limited, but live vaccines are avoided during treatment.
What this interaction means in plain words
Measles vaccine and Secukinumab can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Why it happens
Immunomodulation by IL-17A blockade may reduce vaccine immunogenicity and impair control of live attenuated virus.
What to do
Complete measles immunization at least several weeks before starting secukinumab where possible. Avoid giving it during treatment.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Other interactions of Secukinumab
- Adenovirus types 4 and 7 live + Secukinumab Major
- Bcg vaccine live + Secukinumab Major
- Influenza virus vaccine quadrivalent intranasal + Secukinumab Major
- Measles mumps and rubella vaccine live + Secukinumab Major
- Measles mumps and rubella vaccine + Secukinumab Major
- Measles mumps rubella and varicella vaccine live + Secukinumab Major
Frequently asked questions
Can I take Measles vaccine with Secukinumab?
MediHelp rates the interaction as major. Measles vaccine and Secukinumab can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Measles vaccine is a live attenuated vaccine, and secukinumab may blunt the immune response or increase the risk of vaccine-related infection. Clinical data are limited, but live vaccines are avoided during treatment.
How serious is the interaction between Measles vaccine and Secukinumab?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Complete measles immunization at least several weeks before starting secukinumab where possible. Avoid giving it during treatment.
What other medicines interact with Secukinumab?
MediHelp also lists interactions of Secukinumab with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Secukinumab page.
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