Drug interactions
Measles mumps and rubella vaccine + Secukinumab
Severity: Major
Measles mumps and rubella vaccine and Secukinumab: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Secukinumab blocks interleukin-17A and may modify immune responses. Labeling advises against live vaccines during therapy because of the lack of safety data and the possibility of reduced response or vaccine-strain infection.
What this interaction means in plain words
Measles mumps and rubella vaccine and Secukinumab can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Measles mumps and rubella vaccine belongs to Miscellaneous; Secukinumab belongs to Miscellaneous.
Why it happens
IL-17A inhibition may alter immune defense, and the effect on live attenuated virus handling is not fully characterized.
What to do
Complete age-appropriate vaccinations, including live vaccines, before starting secukinumab. Avoid live vaccines during treatment.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Measles mumps and rubella vaccine and Secukinumab, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Measles mumps and rubella vaccine
- Adalimumab + Measles mumps and rubella vaccine Contraindicated
- Anakinra + Measles mumps and rubella vaccine Contraindicated
- Antithymocyte globulin equine + Measles mumps and rubella vaccine Contraindicated
- Antithymocyte globulin rabbit + Measles mumps and rubella vaccine Contraindicated
- Azathioprine + Measles mumps and rubella vaccine Contraindicated
- Basiliximab + Measles mumps and rubella vaccine Contraindicated
Other interactions of Secukinumab
- Adenovirus types 4 and 7 live + Secukinumab Major
- Bcg vaccine live + Secukinumab Major
- Influenza virus vaccine quadrivalent intranasal + Secukinumab Major
- Measles mumps and rubella vaccine live + Secukinumab Major
- Measles mumps rubella and varicella vaccine live + Secukinumab Major
- Measles vaccine + Secukinumab Major
Frequently asked questions
Can I take Measles mumps and rubella vaccine with Secukinumab?
MediHelp rates the interaction as major. Measles mumps and rubella vaccine and Secukinumab can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Secukinumab blocks interleukin-17A and may modify immune responses. Labeling advises against live vaccines during therapy because of the lack of safety data and the possibility of reduced response or vaccine-strain infection.
How serious is the interaction between Measles mumps and rubella vaccine and Secukinumab?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Complete age-appropriate vaccinations, including live vaccines, before starting secukinumab. Avoid live vaccines during treatment.
What other medicines interact with Measles mumps and rubella vaccine?
MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
