Drug interactions
Meningococcal a c y and w-135 polysaccharide vaccine combined + Secukinumab
Severity: Minor
Meningococcal a c y and w-135 polysaccharide vaccine combined and Secukinumab: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Non-live vaccines are not contraindicated with secukinumab, but the response may be reduced. Because meningococcal disease is serious, adequate immunity is important.
What this interaction means in plain words
Meningococcal a c y and w-135 polysaccharide vaccine combined and Secukinumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
IL-17A inhibition may modestly blunt immune responses to non-live vaccines.
What to do
Vaccinate before starting secukinumab when possible; vaccination during therapy is acceptable if indicated.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Secukinumab
- Adenovirus types 4 and 7 live + Secukinumab Major
- Bcg vaccine live + Secukinumab Major
- Influenza virus vaccine quadrivalent intranasal + Secukinumab Major
- Measles mumps and rubella vaccine live + Secukinumab Major
- Measles mumps and rubella vaccine + Secukinumab Major
- Measles mumps rubella and varicella vaccine live + Secukinumab Major
Frequently asked questions
Can I take Meningococcal a c y and w-135 polysaccharide vaccine combined with Secukinumab?
MediHelp rates the interaction as minor. Meningococcal a c y and w-135 polysaccharide vaccine combined and Secukinumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Non-live vaccines are not contraindicated with secukinumab, but the response may be reduced. Because meningococcal disease is serious, adequate immunity is important.
How serious is the interaction between Meningococcal a c y and w-135 polysaccharide vaccine combined and Secukinumab?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate before starting secukinumab when possible; vaccination during therapy is acceptable if indicated.
What other medicines interact with Secukinumab?
MediHelp also lists interactions of Secukinumab with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Secukinumab page.
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