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Drug interactions

Mesterolone + Tolazamide

Severity: Minor

Mesterolone and Tolazamide: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Androgens may lower blood glucose and could add to the effect of tolazamide, modestly raising hypoglycemia risk.

What this interaction means in plain words

Mesterolone and Tolazamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Mesterolone belongs to Endocrine; Tolazamide belongs to Endocrine.

Evidence level: Low

Why it happens

Androgens may enhance insulin sensitivity, giving an additive glucose-lowering effect.

What to do

Monitor blood glucose when mesterolone is started or stopped. Lower the tolazamide dose if hypoglycemia occurs.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Mesterolone with Tolazamide?

MediHelp rates the interaction as minor. Mesterolone and Tolazamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Androgens may lower blood glucose and could add to the effect of tolazamide, modestly raising hypoglycemia risk.

How serious is the interaction between Mesterolone and Tolazamide?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when mesterolone is started or stopped. Lower the tolazamide dose if hypoglycemia occurs.

What other medicines interact with Tolazamide?

MediHelp also lists interactions of Tolazamide with, for example, Disopyramide, Insulin degludec-liraglutide, Aceclofenac. The full list is on the Tolazamide page.

Full monographs, dosing and an interaction checker in the MediHelp app

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