Drug interactions
Metformin-pioglitazone + Vortioxetine
Severity: Minor
Metformin-pioglitazone and Vortioxetine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
No well-documented interaction exists between vortioxetine and metformin or pioglitazone. Antidepressants may rarely influence glycemic control.
What this interaction means in plain words
Metformin-pioglitazone and Vortioxetine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Metformin-pioglitazone belongs to Endocrine; Vortioxetine belongs to Central Nervous System.
Why it happens
Not established; possible minor effects on glucose homeostasis.
What to do
Routine glucose monitoring is sufficient.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Metformin-pioglitazone
Other interactions of Vortioxetine
- Isocarboxazid + Vortioxetine Contraindicated
- Linezolid + Vortioxetine Contraindicated
- Methylene blue + Vortioxetine Contraindicated
- Phenelzine + Vortioxetine Contraindicated
- Rasagiline + Vortioxetine Contraindicated
- Selegiline transdermal + Vortioxetine Contraindicated
Frequently asked questions
Can I take Metformin-pioglitazone with Vortioxetine?
MediHelp rates the interaction as minor. Metformin-pioglitazone and Vortioxetine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. No well-documented interaction exists between vortioxetine and metformin or pioglitazone. Antidepressants may rarely influence glycemic control.
How serious is the interaction between Metformin-pioglitazone and Vortioxetine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Routine glucose monitoring is sufficient.
What other medicines interact with Metformin-pioglitazone?
MediHelp also lists interactions of Metformin-pioglitazone with, for example, Contrast media, Diatrizoate meglumine / diatrizoate, Diatrizoate. The full list is on the Metformin-pioglitazone page.
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