Drug interactions
Metformin-repaglinide + Methamphetamine
Severity: Moderate
Metformin-repaglinide and Methamphetamine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sympathomimetic stimulants like methamphetamine can raise blood glucose and alter appetite and eating patterns, affecting diabetes control. Glycemic variability and hypoglycemia from erratic food intake can occur.
What this interaction means in plain words
Metformin-repaglinide and Methamphetamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Metformin-repaglinide belongs to Endocrine; Methamphetamine belongs to Central Nervous System.
Why it happens
Sympathomimetic stimulation promotes glycogenolysis and counter-regulatory hormone release, opposing antidiabetic effects.
What to do
Monitor blood glucose and adjust antidiabetic therapy if control changes.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Metformin-repaglinide
Other interactions of Methamphetamine
- Isocarboxazid + Methamphetamine Contraindicated
- Linezolid + Methamphetamine Contraindicated
- Methamphetamine + Phenelzine Contraindicated
- Methamphetamine + Procarbazine Contraindicated
- Methamphetamine + Rasagiline Contraindicated
- Methamphetamine + Safinamide Contraindicated
Frequently asked questions
Can I take Metformin-repaglinide with Methamphetamine?
MediHelp rates the interaction as moderate. Metformin-repaglinide and Methamphetamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sympathomimetic stimulants like methamphetamine can raise blood glucose and alter appetite and eating patterns, affecting diabetes control. Glycemic variability and hypoglycemia from erratic food intake can occur.
How serious is the interaction between Metformin-repaglinide and Methamphetamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose and adjust antidiabetic therapy if control changes.
What other medicines interact with Metformin-repaglinide?
MediHelp also lists interactions of Metformin-repaglinide with, for example, Gemfibrozil, Apalutamide, Clarithromycin. The full list is on the Metformin-repaglinide page.
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