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Drug interactions

Metformin-repaglinide + Tedizolid

Severity: Minor

Metformin-repaglinide and Tedizolid: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

No clinically established interaction exists between tedizolid and metformin or repaglinide. Tedizolid is a weak reversible MAO inhibitor, and linezolid-like agents have occasionally been linked to hypoglycemia in diabetic patients.

What this interaction means in plain words

Metformin-repaglinide and Tedizolid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Metformin-repaglinide belongs to Endocrine; Tedizolid belongs to Anti Bacterial.

Evidence level: Low

Why it happens

The mechanism is not established; possible weak MAO inhibition may influence glucose regulation.

What to do

Monitor blood glucose during tedizolid therapy and adjust antidiabetic doses if hypoglycemia appears.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Metformin-repaglinide with Tedizolid?

MediHelp rates the interaction as minor. Metformin-repaglinide and Tedizolid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. No clinically established interaction exists between tedizolid and metformin or repaglinide. Tedizolid is a weak reversible MAO inhibitor, and linezolid-like agents have occasionally been linked to hypoglycemia in diabetic patients.

How serious is the interaction between Metformin-repaglinide and Tedizolid?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose during tedizolid therapy and adjust antidiabetic doses if hypoglycemia appears.

What other medicines interact with Metformin-repaglinide?

MediHelp also lists interactions of Metformin-repaglinide with, for example, Gemfibrozil, Apalutamide, Clarithromycin. The full list is on the Metformin-repaglinide page.

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