Drug interactions
Metoclopramide + Quazepam
Severity: Moderate
Metoclopramide and Quazepam: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs cause sedation, so combined use can increase drowsiness, dizziness and psychomotor impairment. Metoclopramide may also hasten absorption of some oral drugs.
What this interaction means in plain words
Metoclopramide and Quazepam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive CNS depressant effects.
What to do
Counsel on additive sedation and advise against driving until response is known. Reduce the benzodiazepine dose if needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Metoclopramide
Frequently asked questions
Can I take Metoclopramide with Quazepam?
MediHelp rates the interaction as moderate. Metoclopramide and Quazepam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs cause sedation, so combined use can increase drowsiness, dizziness and psychomotor impairment. Metoclopramide may also hasten absorption of some oral drugs.
How serious is the interaction between Metoclopramide and Quazepam?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel on additive sedation and advise against driving until response is known. Reduce the benzodiazepine dose if needed.
What other medicines interact with Metoclopramide?
MediHelp also lists interactions of Metoclopramide with, for example, Amantadine, Amoxapine, Antipsychotics (e.g., haloperidol). The full list is on the Metoclopramide page.
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