Drug interactions
Metoclopramide + Valerian
Severity: Minor
Metoclopramide and Valerian: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Valerian has sedative properties that may add to the drowsiness caused by metoclopramide. The clinical data are limited and the effect is generally mild.
What this interaction means in plain words
Metoclopramide and Valerian have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive CNS depression via GABAergic effects of valerian.
What to do
Advise the patient about additive drowsiness and caution with driving. Stopping valerian is enough if excess sedation develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Metoclopramide and Valerian, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Metoclopramide
Frequently asked questions
Can I take Metoclopramide with Valerian?
MediHelp rates the interaction as minor. Metoclopramide and Valerian have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Valerian has sedative properties that may add to the drowsiness caused by metoclopramide. The clinical data are limited and the effect is generally mild.
How serious is the interaction between Metoclopramide and Valerian?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise the patient about additive drowsiness and caution with driving. Stopping valerian is enough if excess sedation develops.
What other medicines interact with Metoclopramide?
MediHelp also lists interactions of Metoclopramide with, for example, Amantadine, Amoxapine, Antipsychotics (e.g., haloperidol). The full list is on the Metoclopramide page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
