Drug interactions
metoprolol + verapamil
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
Bradycardia/AV block; heart failure decompensation.
Mechanism of action
Additive AV nodal blockade.
Clinical management
Avoid in conduction disease; monitor HR/BP.
Drug reference
References
Frequently asked questions
Can I take metoprolol with verapamil?
The interaction is rated: Major. Bradycardia/AV block; heart failure decompensation.
How serious is the interaction between metoprolol and verapamil?
The interaction is rated: Major. Evidence level: High.
How is the interaction between metoprolol and verapamil managed?
Avoid in conduction disease; monitor HR/BP.
Why do metoprolol and verapamil interact?
Additive AV nodal blockade.
Full monographs, dosing and an interaction checker in the MediHelp app
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