Drug interactions
Micafungin + Nifedipine
Severity: Minor
Micafungin and Nifedipine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Micafungin has been reported to modestly raise nifedipine exposure in pharmacokinetic studies. The clinical effect is generally small but could add to blood pressure lowering, flushing or edema in sensitive patients.
What this interaction means in plain words
Micafungin and Nifedipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Micafungin belongs to Anti Fungals; Nifedipine belongs to Cardiovascular.
Why it happens
Possible weak inhibition of CYP3A4-mediated nifedipine metabolism; the mechanism is not firmly established.
What to do
Monitor blood pressure and signs of vasodilatory adverse effects such as edema and headache when micafungin is started. Reduce the nifedipine dose only if symptomatic hypotension occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Micafungin
- Lomitapide + Micafungin Moderate
- Micafungin + Saccharomyces boulardii Moderate
- Micafungin + Sirolimus Moderate
- Avapritinib + Micafungin Minor
- Finerenone + Micafungin Minor
- Isavuconazonium + Micafungin Minor
Other interactions of Nifedipine
Frequently asked questions
Can I take Micafungin with Nifedipine?
MediHelp rates the interaction as minor. Micafungin and Nifedipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Micafungin has been reported to modestly raise nifedipine exposure in pharmacokinetic studies. The clinical effect is generally small but could add to blood pressure lowering, flushing or edema in sensitive patients.
How serious is the interaction between Micafungin and Nifedipine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and signs of vasodilatory adverse effects such as edema and headache when micafungin is started. Reduce the nifedipine dose only if symptomatic hypotension occurs.
What other medicines interact with Micafungin?
MediHelp also lists interactions of Micafungin with, for example, Lomitapide, Saccharomyces boulardii, Sirolimus. The full list is on the Micafungin page.
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