Drug interactions
Midodrine + Quinine
Severity: Minor
Midodrine and Quinine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Midodrine and quinine are both basic compounds that may compete for renal tubular secretion, but the effect on quinine levels is expected to be minimal.
What this interaction means in plain words
Midodrine and Quinine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Midodrine belongs to Miscellaneous; Quinine belongs to Anti Parasitic.
Why it happens
Possible competition for renal tubular cationic secretion.
What to do
No action is generally required; monitor blood pressure and quinine tolerance as usual.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Quinine
- Arsenic trioxide + Quinine Contraindicated
- Dofetilide + Quinine Contraindicated
- Dronedarone + Quinine Contraindicated
- Ibutilide + Quinine Contraindicated
- Mefloquine + Quinine Contraindicated
- Nilotinib + Quinine Contraindicated
Other interactions of Midodrine
- Isocarboxazid + Midodrine Contraindicated
- Midodrine + Phenelzine Contraindicated
- Midodrine + Tranylcypromine Contraindicated
- Dextroamphetamine + Midodrine Major
- Dihydroergotamine intranasal + Midodrine Major
- Dihydroergotamine + Midodrine Major
Frequently asked questions
Can I take Midodrine with Quinine?
MediHelp rates the interaction as minor. Midodrine and Quinine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Midodrine and quinine are both basic compounds that may compete for renal tubular secretion, but the effect on quinine levels is expected to be minimal.
How serious is the interaction between Midodrine and Quinine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is generally required; monitor blood pressure and quinine tolerance as usual.
What other medicines interact with Quinine?
MediHelp also lists interactions of Quinine with, for example, Arsenic trioxide, Dofetilide, Dronedarone. The full list is on the Quinine page.
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