Drug interactions
Modafinil + Salbutamol
Severity: Minor
Modafinil and Salbutamol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Modafinil is a wake-promoting agent that can raise heart rate and blood pressure, and salbutamol can add to these effects and cause tremor or nervousness. The combination is usually tolerated but may bother sensitive patients.
What this interaction means in plain words
Modafinil and Salbutamol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Modafinil belongs to Central Nervous System; Salbutamol belongs to Respiratory.
Why it happens
Additive central and cardiovascular stimulation; no pharmacokinetic interaction is established.
What to do
Monitor heart rate, blood pressure and symptoms such as palpitations or jitteriness. Adjust doses if these become troublesome.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Salbutamol
Other interactions of Modafinil
Frequently asked questions
Can I take Modafinil with Salbutamol?
MediHelp rates the interaction as minor. Modafinil and Salbutamol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Modafinil is a wake-promoting agent that can raise heart rate and blood pressure, and salbutamol can add to these effects and cause tremor or nervousness. The combination is usually tolerated but may bother sensitive patients.
How serious is the interaction between Modafinil and Salbutamol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, blood pressure and symptoms such as palpitations or jitteriness. Adjust doses if these become troublesome.
What other medicines interact with Salbutamol?
MediHelp also lists interactions of Salbutamol with, for example, Arsenic trioxide, Carvedilol, Droperidol. The full list is on the Salbutamol page.
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