Drug interactions
Mycophenolate mofetil + Pneumococcal vaccine 13-valent
Severity: Minor
Mycophenolate mofetil and Pneumococcal vaccine 13-valent: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Mycophenolate can lower antibody responses to pneumococcal vaccination. The vaccine is inactivated, so it can still be given and is recommended.
What this interaction means in plain words
Mycophenolate mofetil and Pneumococcal vaccine 13-valent have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Mycophenolate mofetil belongs to Miscellaneous; Pneumococcal vaccine 13-valent belongs to Miscellaneous.
Why it happens
Inhibition of lymphocyte proliferation reduces vaccine immunogenicity.
What to do
Vaccinate per schedule, ideally before starting mycophenolate. Do not withhold the vaccine.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Mycophenolate mofetil
- Adenovirus types 4 and 7 live + Mycophenolate mofetil Contraindicated
- Bcg vaccine live + Mycophenolate mofetil Contraindicated
- Influenza virus vaccine quadrivalent intranasal + Mycophenolate mofetil Contraindicated
- Measles mumps and rubella vaccine live + Mycophenolate mofetil Contraindicated
- Measles mumps rubella and varicella vaccine live + Mycophenolate mofetil Contraindicated
- Measles vaccine + Mycophenolate mofetil Contraindicated
Other interactions of Pneumococcal vaccine 13-valent
- Adalimumab + Pneumococcal vaccine 13-valent Moderate
- Alefacept + Pneumococcal vaccine 13-valent Moderate
- Anakinra + Pneumococcal vaccine 13-valent Moderate
- Anti-thymocyte + Pneumococcal vaccine 13-valent Moderate
- Antithymocyte globulin equine + Pneumococcal vaccine 13-valent Moderate
- Antithymocyte globulin rabbit + Pneumococcal vaccine 13-valent Moderate
Frequently asked questions
Can I take Mycophenolate mofetil with Pneumococcal vaccine 13-valent?
MediHelp rates the interaction as minor. Mycophenolate mofetil and Pneumococcal vaccine 13-valent have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Mycophenolate can lower antibody responses to pneumococcal vaccination. The vaccine is inactivated, so it can still be given and is recommended.
How serious is the interaction between Mycophenolate mofetil and Pneumococcal vaccine 13-valent?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate per schedule, ideally before starting mycophenolate. Do not withhold the vaccine.
What other medicines interact with Mycophenolate mofetil?
MediHelp also lists interactions of Mycophenolate mofetil with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Mycophenolate mofetil page.
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