Drug interactions
Neomycin + Torsemide
Severity: Moderate
Neomycin and Torsemide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Loop diuretics can add to aminoglycoside hearing damage and kidney toxicity. With oral neomycin this is relevant mainly when absorption is increased by renal impairment, bowel inflammation or prolonged use.
What this interaction means in plain words
Neomycin and Torsemide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Neomycin belongs to Anti Bacterial; Torsemide belongs to Cardiovascular.
Why it happens
Additive ototoxicity and nephrotoxicity, with volume depletion raising exposure to absorbed neomycin.
What to do
Monitor renal function and hearing if neomycin is used long term or in renal impairment. Maintain hydration and avoid high doses.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Neomycin
- Amikacin + Neomycin Major
- Amphotericin b deoxycholate + Neomycin Major
- Capreomycin + Neomycin Major
- Cidofovir + Neomycin Major
- Colistin + Neomycin Major
- Ethacrynic acid + Neomycin Major
Other interactions of Torsemide
Frequently asked questions
Can I take Neomycin with Torsemide?
MediHelp rates the interaction as moderate. Neomycin and Torsemide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Loop diuretics can add to aminoglycoside hearing damage and kidney toxicity. With oral neomycin this is relevant mainly when absorption is increased by renal impairment, bowel inflammation or prolonged use.
How serious is the interaction between Neomycin and Torsemide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function and hearing if neomycin is used long term or in renal impairment. Maintain hydration and avoid high doses.
What other medicines interact with Neomycin?
MediHelp also lists interactions of Neomycin with, for example, Amikacin, Amphotericin b deoxycholate, Capreomycin. The full list is on the Neomycin page.
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