Drug interactions
Ofloxacin + Triclabendazole
Severity: Moderate
Ofloxacin and Triclabendazole: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs may prolong the QT interval, so combined use may increase the risk of ventricular arrhythmia. Risk is greater with electrolyte disturbances or heart disease.
What this interaction means in plain words
Ofloxacin and Triclabendazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ofloxacin belongs to Anti Bacterial; Triclabendazole belongs to Anti Parasitic.
Why it happens
Additive prolongation of cardiac repolarization.
What to do
Obtain an ECG and correct electrolytes in patients with cardiac risk factors. Choose a non-QT-prolonging antibiotic if possible.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ofloxacin
- Ofloxacin + Thioridazine Contraindicated
- Adagrasib + Ofloxacin Major
- Amiodarone + Ofloxacin Major
- Amisulpride + Ofloxacin Major
- Anagrelide + Ofloxacin Major
- Arsenic trioxide + Ofloxacin Major
Other interactions of Triclabendazole
Frequently asked questions
Can I take Ofloxacin with Triclabendazole?
MediHelp rates the interaction as moderate. Ofloxacin and Triclabendazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs may prolong the QT interval, so combined use may increase the risk of ventricular arrhythmia. Risk is greater with electrolyte disturbances or heart disease.
How serious is the interaction between Ofloxacin and Triclabendazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain an ECG and correct electrolytes in patients with cardiac risk factors. Choose a non-QT-prolonging antibiotic if possible.
What other medicines interact with Ofloxacin?
MediHelp also lists interactions of Ofloxacin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Ofloxacin page.
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