Drug interactions
Olopatadine intranasal + Vilazodone
Severity: Minor
Olopatadine intranasal and Vilazodone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Intranasal olopatadine can cause somnolence and may add to the sedative effects of CNS-active drugs. Vilazodone can cause drowsiness in some patients, so psychomotor impairment may be somewhat greater.
What this interaction means in plain words
Olopatadine intranasal and Vilazodone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive CNS depression from antihistaminic sedation and antidepressant effects.
What to do
Advise patients about drowsiness and caution when driving. Take olopatadine at the labeled dose.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Vilazodone
- Isocarboxazid + Vilazodone Contraindicated
- Methylene blue + Vilazodone Contraindicated
- Phenelzine + Vilazodone Contraindicated
- Rasagiline + Vilazodone Contraindicated
- Selegiline transdermal + Vilazodone Contraindicated
- Selegiline + Vilazodone Contraindicated
Frequently asked questions
Can I take Olopatadine intranasal with Vilazodone?
MediHelp rates the interaction as minor. Olopatadine intranasal and Vilazodone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Intranasal olopatadine can cause somnolence and may add to the sedative effects of CNS-active drugs. Vilazodone can cause drowsiness in some patients, so psychomotor impairment may be somewhat greater.
How serious is the interaction between Olopatadine intranasal and Vilazodone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients about drowsiness and caution when driving. Take olopatadine at the labeled dose.
What other medicines interact with Vilazodone?
MediHelp also lists interactions of Vilazodone with, for example, Isocarboxazid, Methylene blue, Phenelzine. The full list is on the Vilazodone page.
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