Drug interactions
Omaveloxolone + Quinine
Severity: Minor
Omaveloxolone and Quinine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Omaveloxolone may weakly induce CYP3A4 and could lower quinine exposure. The clinical importance is uncertain, but reduced antimalarial efficacy is possible.
What this interaction means in plain words
Omaveloxolone and Quinine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Omaveloxolone belongs to Central Nervous System; Quinine belongs to Anti Parasitic.
Why it happens
Possible weak CYP3A4 induction by omaveloxolone increases quinine metabolism.
What to do
No dose change is needed routinely. Monitor clinical response to quinine.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Quinine
- Arsenic trioxide + Quinine Contraindicated
- Dofetilide + Quinine Contraindicated
- Dronedarone + Quinine Contraindicated
- Ibutilide + Quinine Contraindicated
- Mefloquine + Quinine Contraindicated
- Nilotinib + Quinine Contraindicated
Other interactions of Omaveloxolone
Frequently asked questions
Can I take Omaveloxolone with Quinine?
MediHelp rates the interaction as minor. Omaveloxolone and Quinine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Omaveloxolone may weakly induce CYP3A4 and could lower quinine exposure. The clinical importance is uncertain, but reduced antimalarial efficacy is possible.
How serious is the interaction between Omaveloxolone and Quinine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed routinely. Monitor clinical response to quinine.
What other medicines interact with Quinine?
MediHelp also lists interactions of Quinine with, for example, Arsenic trioxide, Dofetilide, Dronedarone. The full list is on the Quinine page.
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