Drug interactions
Oxaliplatin + Teicoplanin
Severity: Moderate
Oxaliplatin and Teicoplanin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can injure the kidneys, and teicoplanin may add to ototoxic risk. Concurrent use may increase the likelihood of renal impairment, which can in turn alter drug clearance.
What this interaction means in plain words
Oxaliplatin and Teicoplanin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Oxaliplatin belongs to Oncology; Teicoplanin belongs to Anti Bacterial.
Why it happens
Additive nephrotoxicity and possibly ototoxicity through overlapping pharmacodynamic effects.
What to do
Monitor serum creatinine and electrolytes regularly, and consider teicoplanin trough levels. Adjust doses for renal function and report hearing changes.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Oxaliplatin
- Adenovirus types 4 and 7 live + Oxaliplatin Contraindicated
- Bcg vaccine live + Oxaliplatin Contraindicated
- Influenza virus vaccine quadrivalent intranasal + Oxaliplatin Contraindicated
- Measles mumps and rubella vaccine live + Oxaliplatin Contraindicated
- Measles mumps and rubella vaccine + Oxaliplatin Contraindicated
- Measles mumps rubella and varicella vaccine live + Oxaliplatin Contraindicated
Other interactions of Teicoplanin
- Amphotericin b + Teicoplanin Major
- Cidofovir + Teicoplanin Major
- Neomycin + Teicoplanin Major
- Teicoplanin + Tobramycin Major
- Acyclovir + Teicoplanin Moderate
- Adefovir + Teicoplanin Moderate
Frequently asked questions
Can I take Oxaliplatin with Teicoplanin?
MediHelp rates the interaction as moderate. Oxaliplatin and Teicoplanin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can injure the kidneys, and teicoplanin may add to ototoxic risk. Concurrent use may increase the likelihood of renal impairment, which can in turn alter drug clearance.
How serious is the interaction between Oxaliplatin and Teicoplanin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and electrolytes regularly, and consider teicoplanin trough levels. Adjust doses for renal function and report hearing changes.
What other medicines interact with Oxaliplatin?
MediHelp also lists interactions of Oxaliplatin with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Oxaliplatin page.
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