Drug interactions
Oxaprozin + Potassium iodide
Severity: Minor
Oxaprozin and Potassium iodide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Potassium iodide supplies potassium, and NSAIDs reduce renal potassium excretion through suppression of renin and aldosterone. Hyperkalemia is possible with prolonged or high-dose use, mainly in patients with renal impairment.
What this interaction means in plain words
Oxaprozin and Potassium iodide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Oxaprozin belongs to Musculoskeletal; Potassium iodide belongs to Endocrine.
Why it happens
Potassium load combined with NSAID-induced reduction in renal potassium excretion.
What to do
No action is needed for short courses in patients with normal renal function. Check serum potassium in patients with kidney disease or other hyperkalemia risk factors.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Oxaprozin
- Ketorolac intranasal + Oxaprozin Contraindicated
- Ketorolac + Oxaprozin Contraindicated
- Aceclofenac + Oxaprozin Major
- Acemetacin + Oxaprozin Major
- Acetylsalicylic acid + Oxaprozin Major
- Alteplase + Oxaprozin Major
Other interactions of Potassium iodide
- Amiloride + Potassium iodide Moderate
- Amlodipine-benazepril + Potassium iodide Moderate
- Amlodipine-hydrochlorothiazide-valsartan + Potassium iodide Moderate
- Amlodipine-olmesartan-hydrochlorothiazide + Potassium iodide Moderate
- Amlodipine-olmesartan + Potassium iodide Moderate
- Amlodipine-perindopril + Potassium iodide Moderate
Frequently asked questions
Can I take Oxaprozin with Potassium iodide?
MediHelp rates the interaction as minor. Oxaprozin and Potassium iodide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Potassium iodide supplies potassium, and NSAIDs reduce renal potassium excretion through suppression of renin and aldosterone. Hyperkalemia is possible with prolonged or high-dose use, mainly in patients with renal impairment.
How serious is the interaction between Oxaprozin and Potassium iodide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action is needed for short courses in patients with normal renal function. Check serum potassium in patients with kidney disease or other hyperkalemia risk factors.
What other medicines interact with Oxaprozin?
MediHelp also lists interactions of Oxaprozin with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Oxaprozin page.
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