Drug interactions
Papaverine + Ziprasidone
Severity: Minor
Papaverine and Ziprasidone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
No well-established sedative interaction exists for this pair, and papaverine is not a significant sedative. Any additive effect would be minor, though both may lower blood pressure.
What this interaction means in plain words
Papaverine and Ziprasidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Papaverine belongs to Cardiovascular; Ziprasidone belongs to Central Nervous System.
Why it happens
Possible additive vasodilatory or hypotensive effects; no established mechanism for sedation.
What to do
Monitor blood pressure and watch for dizziness when the two are used together.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ziprasidone
- Amiodarone + Ziprasidone Contraindicated
- Amitriptyline + Ziprasidone Contraindicated
- Arsenic trioxide + Ziprasidone Contraindicated
- Bedaquiline + Ziprasidone Contraindicated
- Chloroquine + Ziprasidone Contraindicated
- Citalopram + Ziprasidone Contraindicated
Other interactions of Papaverine
- Givinostat + Papaverine Major
- Bretylium + Papaverine Moderate
- Calcium / magnesium / potassium / sodium oxybates + Papaverine Moderate
- Carbidopa-entacapone-levodopa + Papaverine Moderate
- Carbidopa-levodopa + Papaverine Moderate
- Carbidopa + Papaverine Moderate
Frequently asked questions
Can I take Papaverine with Ziprasidone?
MediHelp rates the interaction as minor. Papaverine and Ziprasidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. No well-established sedative interaction exists for this pair, and papaverine is not a significant sedative. Any additive effect would be minor, though both may lower blood pressure.
How serious is the interaction between Papaverine and Ziprasidone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and watch for dizziness when the two are used together.
What other medicines interact with Ziprasidone?
MediHelp also lists interactions of Ziprasidone with, for example, Amiodarone, Amitriptyline, Arsenic trioxide. The full list is on the Ziprasidone page.
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