Drug interactions
Pneumococcal vaccine polyvalent + Secukinumab
Severity: Minor
Pneumococcal vaccine polyvalent and Secukinumab: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Pneumococcal vaccination is not contraindicated with secukinumab, but antibody responses may be somewhat reduced. Patients on biologics are at higher infection risk, so vaccination remains important.
What this interaction means in plain words
Pneumococcal vaccine polyvalent and Secukinumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
IL-17A inhibition may modestly blunt immune responses to non-live vaccines.
What to do
Give pneumococcal vaccination ideally before starting secukinumab; it can be given during therapy if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Secukinumab
- Adenovirus types 4 and 7 live + Secukinumab Major
- Bcg vaccine live + Secukinumab Major
- Influenza virus vaccine quadrivalent intranasal + Secukinumab Major
- Measles mumps and rubella vaccine live + Secukinumab Major
- Measles mumps and rubella vaccine + Secukinumab Major
- Measles mumps rubella and varicella vaccine live + Secukinumab Major
Frequently asked questions
Can I take Pneumococcal vaccine polyvalent with Secukinumab?
MediHelp rates the interaction as minor. Pneumococcal vaccine polyvalent and Secukinumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Pneumococcal vaccination is not contraindicated with secukinumab, but antibody responses may be somewhat reduced. Patients on biologics are at higher infection risk, so vaccination remains important.
How serious is the interaction between Pneumococcal vaccine polyvalent and Secukinumab?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give pneumococcal vaccination ideally before starting secukinumab; it can be given during therapy if needed.
What other medicines interact with Secukinumab?
MediHelp also lists interactions of Secukinumab with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Secukinumab page.
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