Drug interactions
Prochlorperazine + Scullcap
Severity: Minor
Prochlorperazine and Scullcap: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Scullcap is used as a mild herbal sedative, so with prochlorperazine it may add to drowsiness and impaired alertness. Evidence is limited and product quality varies.
What this interaction means in plain words
Prochlorperazine and Scullcap have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Presumed additive CNS depressant effects; herbal mechanism is not well established.
What to do
Advise patients about increased drowsiness and caution with driving. Discourage the herbal product if sedation is troublesome.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Prochlorperazine
- Dronedarone + Prochlorperazine Contraindicated
- Ibutilide + Prochlorperazine Contraindicated
- Nilotinib + Prochlorperazine Contraindicated
- Pimozide + Prochlorperazine Contraindicated
- Prochlorperazine + Thioridazine Contraindicated
- Amiodarone + Prochlorperazine Major
Frequently asked questions
Can I take Prochlorperazine with Scullcap?
MediHelp rates the interaction as minor. Prochlorperazine and Scullcap have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Scullcap is used as a mild herbal sedative, so with prochlorperazine it may add to drowsiness and impaired alertness. Evidence is limited and product quality varies.
How serious is the interaction between Prochlorperazine and Scullcap?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients about increased drowsiness and caution with driving. Discourage the herbal product if sedation is troublesome.
What other medicines interact with Prochlorperazine?
MediHelp also lists interactions of Prochlorperazine with, for example, Dronedarone, Ibutilide, Nilotinib. The full list is on the Prochlorperazine page.
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