Drug interactions
Propylhexedrine + Salmeterol
Severity: Minor
Propylhexedrine and Salmeterol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Propylhexedrine is a sympathomimetic nasal decongestant with some systemic absorption, and with salmeterol may add to increases in heart rate and blood pressure. The risk is mainly in patients with cardiovascular disease or overuse of the inhaler.
What this interaction means in plain words
Propylhexedrine and Salmeterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Propylhexedrine belongs to Respiratory; Salmeterol belongs to Respiratory.
Why it happens
Additive sympathomimetic stimulation.
What to do
Use propylhexedrine only as labeled and monitor heart rate and blood pressure in patients with cardiovascular disease.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Salmeterol
- Ritonavir + Salmeterol Contraindicated
- Salmeterol + Saquinavir Contraindicated
- Amitriptyline + Salmeterol Major
- Arformoterol + Salmeterol Major
- Atazanavir + Salmeterol Major
- Budesonide-formoterol + Salmeterol Major
Other interactions of Propylhexedrine
- Isocarboxazid + Propylhexedrine Contraindicated
- Phenelzine + Propylhexedrine Contraindicated
- Linezolid + Propylhexedrine Major
- Propylhexedrine + Selegiline Major
- Propylhexedrine + Tranylcypromine Major
- Adrenaline-articaine + Propylhexedrine Moderate
Frequently asked questions
Can I take Propylhexedrine with Salmeterol?
MediHelp rates the interaction as minor. Propylhexedrine and Salmeterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Propylhexedrine is a sympathomimetic nasal decongestant with some systemic absorption, and with salmeterol may add to increases in heart rate and blood pressure. The risk is mainly in patients with cardiovascular disease or overuse of the inhaler.
How serious is the interaction between Propylhexedrine and Salmeterol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use propylhexedrine only as labeled and monitor heart rate and blood pressure in patients with cardiovascular disease.
What other medicines interact with Salmeterol?
MediHelp also lists interactions of Salmeterol with, for example, Ritonavir, Saquinavir, Amitriptyline. The full list is on the Salmeterol page.
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