Drug interactions
Pseudoephedrine + Tiotropium-olodaterol
Severity: Moderate
Pseudoephedrine and Tiotropium-olodaterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Pseudoephedrine is a sympathomimetic that raises blood pressure and heart rate, and olodaterol adds beta-mediated cardiac stimulation. The combination may cause palpitations, tachycardia, tremor, and hypertension.
What this interaction means in plain words
Pseudoephedrine and Tiotropium-olodaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Pseudoephedrine belongs to Respiratory; Tiotropium-olodaterol belongs to Respiratory.
Why it happens
Additive sympathomimetic stimulation.
What to do
Monitor blood pressure and heart rate and advise patients with cardiovascular disease to avoid oral decongestants. Reduce or stop pseudoephedrine if symptoms occur.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Tiotropium-olodaterol
Other interactions of Pseudoephedrine
- Isocarboxazid + Pseudoephedrine Contraindicated
- Phenelzine + Pseudoephedrine Contraindicated
- Pseudoephedrine + Rasagiline Contraindicated
- Pseudoephedrine + Selegiline Contraindicated
- Pseudoephedrine + Selegiline transdermal Contraindicated
- Pseudoephedrine + Tranylcypromine Contraindicated
Frequently asked questions
Can I take Pseudoephedrine with Tiotropium-olodaterol?
MediHelp rates the interaction as moderate. Pseudoephedrine and Tiotropium-olodaterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Pseudoephedrine is a sympathomimetic that raises blood pressure and heart rate, and olodaterol adds beta-mediated cardiac stimulation. The combination may cause palpitations, tachycardia, tremor, and hypertension.
How serious is the interaction between Pseudoephedrine and Tiotropium-olodaterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate and advise patients with cardiovascular disease to avoid oral decongestants. Reduce or stop pseudoephedrine if symptoms occur.
What other medicines interact with Tiotropium-olodaterol?
MediHelp also lists interactions of Tiotropium-olodaterol with, for example, Amisulpride, Arformoterol, Arsenic trioxide. The full list is on the Tiotropium-olodaterol page.
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