Drug interactions
Quetiapine + Tazemetostat
Severity: Minor
Quetiapine and Tazemetostat: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tazemetostat is a weak to moderate CYP3A4 inducer and may lower quetiapine concentrations. This could reduce antipsychotic effect.
What this interaction means in plain words
Quetiapine and Tazemetostat have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Quetiapine belongs to Central Nervous System; Tazemetostat belongs to Miscellaneous.
Why it happens
Induction of CYP3A4 increases quetiapine clearance.
What to do
Monitor psychiatric response and increase the quetiapine dose if effect is lost.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Quetiapine
- Adagrasib + Quetiapine Major
- Amiodarone + Quetiapine Major
- Amisulpride + Quetiapine Major
- Amoxapine + Quetiapine Major
- Anagrelide + Quetiapine Major
- Apalutamide + Quetiapine Major
Other interactions of Tazemetostat
Frequently asked questions
Can I take Quetiapine with Tazemetostat?
MediHelp rates the interaction as minor. Quetiapine and Tazemetostat have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tazemetostat is a weak to moderate CYP3A4 inducer and may lower quetiapine concentrations. This could reduce antipsychotic effect.
How serious is the interaction between Quetiapine and Tazemetostat?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor psychiatric response and increase the quetiapine dose if effect is lost.
What other medicines interact with Quetiapine?
MediHelp also lists interactions of Quetiapine with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Quetiapine page.
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