Drug interactions
Quinidine + Teduglutide
Severity: Moderate
Quinidine and Teduglutide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Teduglutide improves intestinal fluid and nutrient absorption and can increase the absorption of oral drugs. Quinidine levels may rise, which matters because it has a narrow therapeutic index.
What this interaction means in plain words
Quinidine and Teduglutide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Quinidine belongs to Anti Parasitic; Teduglutide belongs to Endocrine.
Why it happens
Enhanced intestinal absorption from the trophic and fluid-absorbing effects of teduglutide increases quinidine bioavailability.
What to do
Monitor quinidine levels and ECG when teduglutide is started or stopped. Adjust the quinidine dose as needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Quinidine
- Adagrasib + Quinidine Contraindicated
- Arsenic trioxide + Quinidine Contraindicated
- Artemether / lumefantrine + Quinidine Contraindicated
- Chloroquine + Quinidine Contraindicated
- Dofetilide + Quinidine Contraindicated
- Dronedarone + Quinidine Contraindicated
Other interactions of Teduglutide
- Chlordiazepoxide + Teduglutide Moderate
- Clonazepam + Teduglutide Moderate
- Colchicine + Teduglutide Moderate
- Cyclosporin + Teduglutide Moderate
- Digoxin + Teduglutide Moderate
- Ethosuximide + Teduglutide Moderate
Frequently asked questions
Can I take Quinidine with Teduglutide?
MediHelp rates the interaction as moderate. Quinidine and Teduglutide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Teduglutide improves intestinal fluid and nutrient absorption and can increase the absorption of oral drugs. Quinidine levels may rise, which matters because it has a narrow therapeutic index.
How serious is the interaction between Quinidine and Teduglutide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor quinidine levels and ECG when teduglutide is started or stopped. Adjust the quinidine dose as needed.
What other medicines interact with Quinidine?
MediHelp also lists interactions of Quinidine with, for example, Adagrasib, Arsenic trioxide, Artemether / lumefantrine. The full list is on the Quinidine page.
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