Drug interactions
Remimazolam + Vilazodone
Severity: Moderate
Remimazolam and Vilazodone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Remimazolam is a short-acting benzodiazepine sedative that can cause profound sedation and respiratory depression. Other CNS-active drugs such as vilazodone may add to the sedative effect and prolong recovery.
What this interaction means in plain words
Remimazolam and Vilazodone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Remimazolam belongs to Central Nervous System; Vilazodone belongs to Central Nervous System.
Why it happens
Additive CNS depression through pharmacodynamic synergism.
What to do
Titrate remimazolam carefully to effect and continuously monitor oxygen saturation, respiration and level of consciousness during and after the procedure. Reduce doses when other sedatives are also used.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Vilazodone
- Isocarboxazid + Vilazodone Contraindicated
- Methylene blue + Vilazodone Contraindicated
- Phenelzine + Vilazodone Contraindicated
- Rasagiline + Vilazodone Contraindicated
- Selegiline transdermal + Vilazodone Contraindicated
- Selegiline + Vilazodone Contraindicated
Other interactions of Remimazolam
Frequently asked questions
Can I take Remimazolam with Vilazodone?
MediHelp rates the interaction as moderate. Remimazolam and Vilazodone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Remimazolam is a short-acting benzodiazepine sedative that can cause profound sedation and respiratory depression. Other CNS-active drugs such as vilazodone may add to the sedative effect and prolong recovery.
How serious is the interaction between Remimazolam and Vilazodone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Titrate remimazolam carefully to effect and continuously monitor oxygen saturation, respiration and level of consciousness during and after the procedure. Reduce doses when other sedatives are also used.
What other medicines interact with Vilazodone?
MediHelp also lists interactions of Vilazodone with, for example, Isocarboxazid, Methylene blue, Phenelzine. The full list is on the Vilazodone page.
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