Drug interactions
Salbutamol + Toremifene
Severity: Moderate
Salbutamol and Toremifene: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Toremifene prolongs the QT interval in a dose-related way. Salbutamol may add to arrhythmic risk by lowering potassium and increasing heart rate, particularly at high doses.
What this interaction means in plain words
Salbutamol and Toremifene can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Salbutamol belongs to Respiratory; Toremifene belongs to Endocrine.
Why it happens
Additive QT prolongation, with beta-2 agonist induced hypokalemia.
What to do
Correct hypokalemia and hypomagnesemia and monitor ECG if frequent or high-dose salbutamol is needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Salbutamol
Other interactions of Toremifene
- Amiodarone + Toremifene Contraindicated
- Dronedarone + Toremifene Contraindicated
- Nilotinib + Toremifene Contraindicated
- Pimozide + Toremifene Contraindicated
- Quinidine + Toremifene Contraindicated
- Ribociclib + Toremifene Contraindicated
Frequently asked questions
Can I take Salbutamol with Toremifene?
MediHelp rates the interaction as moderate. Salbutamol and Toremifene can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Toremifene prolongs the QT interval in a dose-related way. Salbutamol may add to arrhythmic risk by lowering potassium and increasing heart rate, particularly at high doses.
How serious is the interaction between Salbutamol and Toremifene?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Correct hypokalemia and hypomagnesemia and monitor ECG if frequent or high-dose salbutamol is needed.
What other medicines interact with Salbutamol?
MediHelp also lists interactions of Salbutamol with, for example, Arsenic trioxide, Carvedilol, Droperidol. The full list is on the Salbutamol page.
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