Drug interactions
Quinidine + Toremifene
Severity: Contraindicated
Quinidine and Toremifene: contraindicated interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs prolong the QT interval, so combining them raises the risk of torsades de pointes. Toremifene labeling advises avoiding QT-prolonging drugs.
What this interaction means in plain words
Quinidine and Toremifene are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Quinidine belongs to Anti Parasitic; Toremifene belongs to Endocrine.
Why it happens
Additive prolongation of cardiac repolarization.
What to do
Do not combine. Choose a non-QT-prolonging alternative for one of the drugs.
What to ask your pharmacist
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Other interactions of Quinidine
- Adagrasib + Quinidine Contraindicated
- Arsenic trioxide + Quinidine Contraindicated
- Artemether / lumefantrine + Quinidine Contraindicated
- Chloroquine + Quinidine Contraindicated
- Dofetilide + Quinidine Contraindicated
- Dronedarone + Quinidine Contraindicated
Other interactions of Toremifene
- Amiodarone + Toremifene Contraindicated
- Dronedarone + Toremifene Contraindicated
- Nilotinib + Toremifene Contraindicated
- Pimozide + Toremifene Contraindicated
- Ribociclib + Toremifene Contraindicated
- Thioridazine + Toremifene Contraindicated
Frequently asked questions
Can I take Quinidine with Toremifene?
MediHelp rates the interaction as contraindicated. Quinidine and Toremifene are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both drugs prolong the QT interval, so combining them raises the risk of torsades de pointes. Toremifene labeling advises avoiding QT-prolonging drugs.
How serious is the interaction between Quinidine and Toremifene?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine. Choose a non-QT-prolonging alternative for one of the drugs.
What other medicines interact with Quinidine?
MediHelp also lists interactions of Quinidine with, for example, Adagrasib, Arsenic trioxide, Artemether / lumefantrine. The full list is on the Quinidine page.
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