Drug interactions
Sarecycline + Saxagliptin
Severity: Minor
Sarecycline and Saxagliptin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sarecycline is reported to have weak P-gp inhibition, which could slightly raise saxagliptin levels. Because oral exposure to sarecycline is modest and saxagliptin tolerates small changes, relevance is likely low.
What this interaction means in plain words
Sarecycline and Saxagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Sarecycline belongs to Anti Bacterial; Saxagliptin belongs to Endocrine.
Why it happens
Possible weak inhibition of P-gp efflux of saxagliptin.
What to do
No routine adjustment needed; monitor for saxagliptin adverse effects if symptoms arise.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Saxagliptin
- Albiglutide + Saxagliptin Moderate
- Amlodipine-benazepril + Saxagliptin Moderate
- Aripiprazole + Saxagliptin Moderate
- Asenapine + Saxagliptin Moderate
- Atazanavir + Saxagliptin Moderate
- Benazepril + Saxagliptin Moderate
Other interactions of Sarecycline
- Acitretin + Sarecycline Contraindicated
- Isotretinoin + Sarecycline Major
- Sarecycline + Tretinoin Major
- Aluminum hydroxide + Sarecycline Moderate
- Calcium carbonate + Sarecycline Moderate
- Calcium + Sarecycline Moderate
Frequently asked questions
Can I take Sarecycline with Saxagliptin?
MediHelp rates the interaction as minor. Sarecycline and Saxagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Sarecycline is reported to have weak P-gp inhibition, which could slightly raise saxagliptin levels. Because oral exposure to sarecycline is modest and saxagliptin tolerates small changes, relevance is likely low.
How serious is the interaction between Sarecycline and Saxagliptin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment needed; monitor for saxagliptin adverse effects if symptoms arise.
What other medicines interact with Saxagliptin?
MediHelp also lists interactions of Saxagliptin with, for example, Albiglutide, Amlodipine-benazepril, Aripiprazole. The full list is on the Saxagliptin page.
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