Drug interactions
Sarecycline + Succinylcholine
Severity: Minor
Sarecycline and Succinylcholine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tetracycline class drugs have been reported to weakly potentiate neuromuscular blockade. Sarecycline is used orally for acne at low systemic exposure, so a meaningful effect with succinylcholine is theoretical.
What this interaction means in plain words
Sarecycline and Succinylcholine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Sarecycline belongs to Anti Bacterial; Succinylcholine belongs to Musculoskeletal.
Why it happens
Possible weak neuromuscular blocking activity of tetracyclines, extrapolated from class data; not established for sarecycline.
What to do
No routine change is needed. Monitor neuromuscular recovery as usual after succinylcholine.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Sarecycline and Succinylcholine, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Succinylcholine
Other interactions of Sarecycline
- Acitretin + Sarecycline Contraindicated
- Isotretinoin + Sarecycline Major
- Sarecycline + Tretinoin Major
- Aluminum hydroxide + Sarecycline Moderate
- Calcium carbonate + Sarecycline Moderate
- Calcium + Sarecycline Moderate
Frequently asked questions
Can I take Sarecycline with Succinylcholine?
MediHelp rates the interaction as minor. Sarecycline and Succinylcholine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tetracycline class drugs have been reported to weakly potentiate neuromuscular blockade. Sarecycline is used orally for acne at low systemic exposure, so a meaningful effect with succinylcholine is theoretical.
How serious is the interaction between Sarecycline and Succinylcholine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed. Monitor neuromuscular recovery as usual after succinylcholine.
What other medicines interact with Succinylcholine?
MediHelp also lists interactions of Succinylcholine with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Capreomycin. The full list is on the Succinylcholine page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
