Drug interactions
Secukinumab + Tetanus toxoid adsorbed or fluid
Severity: Minor
Secukinumab and Tetanus toxoid adsorbed or fluid: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Secukinumab may theoretically weaken the response to tetanus toxoid, but controlled data with tetanus vaccine during secukinumab therapy showed adequate antibody responses. The vaccine is inactivated and can be given.
What this interaction means in plain words
Secukinumab and Tetanus toxoid adsorbed or fluid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
IL-17A blockade may modulate vaccine immunogenicity, though tetanus responses appear largely preserved.
What to do
Vaccinate on the usual schedule, ideally before starting secukinumab. No dose adjustment is needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Secukinumab
- Adenovirus types 4 and 7 live + Secukinumab Major
- Bcg vaccine live + Secukinumab Major
- Influenza virus vaccine quadrivalent intranasal + Secukinumab Major
- Measles mumps and rubella vaccine live + Secukinumab Major
- Measles mumps and rubella vaccine + Secukinumab Major
- Measles mumps rubella and varicella vaccine live + Secukinumab Major
Frequently asked questions
Can I take Secukinumab with Tetanus toxoid adsorbed or fluid?
MediHelp rates the interaction as minor. Secukinumab and Tetanus toxoid adsorbed or fluid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Secukinumab may theoretically weaken the response to tetanus toxoid, but controlled data with tetanus vaccine during secukinumab therapy showed adequate antibody responses. The vaccine is inactivated and can be given.
How serious is the interaction between Secukinumab and Tetanus toxoid adsorbed or fluid?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate on the usual schedule, ideally before starting secukinumab. No dose adjustment is needed.
What other medicines interact with Secukinumab?
MediHelp also lists interactions of Secukinumab with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Secukinumab page.
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