Drug interactions
Sunitinib + Triclabendazole
Severity: Moderate
Sunitinib and Triclabendazole: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both agents can prolong the QT interval, so concurrent use may increase risk of ventricular arrhythmia.
What this interaction means in plain words
Sunitinib and Triclabendazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Sunitinib belongs to Oncology; Triclabendazole belongs to Anti Parasitic.
Why it happens
Additive effects on cardiac repolarization.
What to do
Obtain baseline ECG and correct electrolyte disturbances. Monitor ECG during the short triclabendazole course in patients with other QT risk factors.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Sunitinib
- Adagrasib + Sunitinib Major
- Amiodarone + Sunitinib Major
- Amisulpride + Sunitinib Major
- Anagrelide + Sunitinib Major
- Apalutamide + Sunitinib Major
- Arsenic trioxide + Sunitinib Major
Other interactions of Triclabendazole
Frequently asked questions
Can I take Sunitinib with Triclabendazole?
MediHelp rates the interaction as moderate. Sunitinib and Triclabendazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both agents can prolong the QT interval, so concurrent use may increase risk of ventricular arrhythmia.
How serious is the interaction between Sunitinib and Triclabendazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain baseline ECG and correct electrolyte disturbances. Monitor ECG during the short triclabendazole course in patients with other QT risk factors.
What other medicines interact with Sunitinib?
MediHelp also lists interactions of Sunitinib with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Sunitinib page.
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